Patane, S., Marte, F., La Rosa, F. C., and Rocca, R. L. Atrial fibrillation associated with chocolate intake abuse and chronic salbutamol inhalation abuse. Suggested Dosage. 1-15-2011;50(2):237-244. 2006;47 Suppl 2:S177-S186. Stopping caffeine too quickly can increase the side effects of lithium. Free Radic Res 2000;33(5):635-641. View abstract. 2013;2013:985087. Adenosine (Adenocard) interacts with COCOA. View abstract. Tomas-Barberan, F. A., Cienfuegos-Jovellanos, E., Marin, A., Muguerza, B., Gil-Izquierdo, A., Cerda, B., Zafrilla, P., Morillas, J., Mulero, J., Ibarra, A., Pasamar, M. A., Ramon, D., and Espin, J. C. A new process to develop a cocoa powder with higher flavonoid monomer content and enhanced bioavailability in healthy humans. I made the mistake of drinking a smoothie made with a cup of cocoa powder recently. Eating cocoa is LIKELY SAFE for most people. Egan, B. M., Laken, M. A., Donovan, J. L., and Woolson, R. F. Does dark chocolate have a role in the prevention and management of hypertension? J Agric.Food Chem. Little is known about how cocoa powder and dark chocolate, rich sources of polyphenols, affect these cardiovascular disease risk factors. The role of fatty acid saturation on plasma lipids, lipoproteins, & apolipoproteins: I. Baba, S., Osakabe, N., Kato, Y., Natsume, M., Yasuda, A., Kido, T., Fukuda, K., Muto, Y., and Kondo, K. Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans. View abstract. Philadelphia, PA: Lippincott Williams & Wilkins; 1998. Institute of Medicine. The caffeine in cocoa might block the affects of dipyridamole (Persantine). Buijsse B, Feskens EJ, Kok FJ, Kromhout D. Cocoa intake, blood pressure, and cardiovascular mortality: the Zutphen Elderly Study. 5-16-2007;55(10):3926-3935. van den Bogaard, B., Draijer, R., Westerhof, B. E., van den Meiracker, A. H., van Montfrans, G. A., and van den Born, B. J. Effects of acute administration of caffeine on vascular function. Some studies have shown that cocoa powder and cocoa flavanols can improve blood flow to the brain, enhancing cognition. Med Sci Sports Exerc 2001;33:1399-403. 2018;195:86-90. Chewing coca leaves could cause : 1. 8-1-2012;69(15):1287-3. Polagruto, J. View abstract. View abstract. View abstract. View abstract. Cocoa is mostly consumed as chocolate, including milk and dark chocolate (white chocolate doesn’t actually have cocoa). Dipyridamole (Persantine) is often used by doctors to do a test on the heart. Taking cocoa (which contains caffeine) along with disulfiram (Antabuse) might increase the effects and side effects of caffeine including jitteriness, hyperactivity, irritability, and others. Cleve Clin J Med 2002;69:449-50. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. J Am Coll.Cardiol. Taking cocoa along with theophylline might increase the effects and side effects of theophylline. Eur.J Nutr 2007;46(1):53-56. Sies, H., Schewe, T., Heiss, C., and Kelm, M. Cocoa polyphenols and inflammatory mediators. J Am.Diet.Assoc. Comparison of the effects of diets rich in stearic acid versus myristic acid and lauric acid on platelet fatty acids and excretion of thromboxane A2 and PGI2 metabolites in healthy young men. Thyroid hormone use and bone mineral density in elderly men. United States Department of Agriculture Research Service. Curr Opin.Lipidol. Effect of caffeine-containing versus decaffeinated coffee on serum clozapine concentrations in hospitalised patients. Cocoa powder is especially high in protein, fiber, and minerals such as iron, copper, magnesium, and manganese. Most research shows that eating dark chocolate or cocoa products for 2-8 weeks can lower the top number in a blood pressure reading (systolic blood pressure) by 4 mmHg. Eur J Epidemiol. J Proteome.Res 2009;8(11):5060-5068. De, Gottardi A., Berzigotti, A., Seijo, S., D'Amico, M., Thormann, W., Abraldes, J. G., Garcia-Pagan, J. C., and Bosch, J. Postprandial effects of dark chocolate on portal hypertension in patients with cirrhosis: results of a phase 2, double-blind, randomized controlled trial. View abstract. Oxid Med Cell Longev. Taking caffeine with some medications for asthma might cause too much stimulation and cause heart problems. View abstract. View abstract. Pakistan J Nutr 2008;7(6):773-781. Erdman, J. W., Jr., Carson, L., Kwik-Uribe, C., Evans, E. M., and Allen, R. R. Effects of cocoa flavanols on risk factors for cardiovascular disease. 2010;23(1):97-103. View abstract. View abstract. View abstract. View abstract. Belz, G. G. and Mohr-Kahaly, S. [Cacoa and dark chocolate in cardiovascular prevention?]. https://ndb.nal.usda.gov/ndb/foods/show/19165. Fluconazole (Diflucan) might decrease how quickly the body gets rid of caffeine. 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